Do I Need Peptides in My Skincare Routine? The Benefits, How to Use Them, and More

October 30th, 2024

By Elena Torano

Scientific Review by Juliana Durack and Larry Weiss

Introduction

When evaluating products for skin longevity, one question that often arises is whether peptides should play a role. Peptides are a gold standard ingredient—these small but powerful compounds deliver a host of rejuvenating benefits to the skin. In this blog, we'll dive deep into what peptides are, the advantages they offer, how to incorporate them into your regimen, and key considerations on ingredient compatibility. We'll also look at whether peptides are suitable for all skin types and introduce you to Symbiome's The Answer Serum.

What Are Peptides?

Peptides are short chains of amino acids, which are the building blocks of collagen and elastin proteins. When applied topically, peptides signal for an increased production of proteins, enhancing structure and reinforcing resilience. There are various types of peptides, each targeting different skin concerns. For example, signal peptides stimulate collagen production, while carrier peptides deliver trace elements essential for skin repair. The versatility of peptides allows them to address a broad range of skin issues, from aging to inflammation.

What Are the Benefits of Peptides in Your Skincare?

Smoothing Fine Lines

Using peptides preventively ensures you don’t see early signs of aging, as you are fortifying your collagen and elastin fibers and thus maintaining skin’s structure. But the firming and plumping benefits of peptides make it essential for repair as well. Visible fine lines and wrinkles start to appear smoother with continued application. 

Soothes Redness and Irritation

Peptides like palmitoyl tetrapeptide-7 have anti-inflammatory properties. You’ll visibly help calm the skin, reduce irritation, and alleviate redness. It’s peace of mind that even those with very sensitive or irritated skin types may use these cellularly communicating peptides. 

Evens Skin Tone and Skin Texture

By now you’re aware that peptides promote skin regeneration. Enhanced cellular turnover helps to fade stubborn hyperpigmentation and smooth rough patches caused by sun exposure and oxidation. 

Strengthens Skin Barrier

The skin’s barrier is crucial for maintaining hydration and protecting against external aggressors. Peptides can help reinforce this barrier, translating to healthier, more resilient skin overall.

What Other Ingredients Can Peptides Be Used With?

Peptides are versatile and can be combined with a wide variety of other skincare serums to maximize their effectiveness.

• Hyaluronic Acid. This popular acid pairs well with peptides by improving surface hydration and plumpness. Hyaluronic acid helps to retain moisture, while peptides work at the deepest layer to promote healthy bounce. 
• Antioxidants. Ingredients like Vitamin C and niacinamide are great companions to peptides, as they provide protection against oxidative stress. With peptides fading existing dark spots, antioxidants prevent new hyperpigmentation from popping up. 
• Glycerin. As a humectant, glycerin draws moisture into the skin. You can soothe and improve overall texture and repair faster with glycerin in the mix. 

What Should You Be Careful Mixing Peptides With?

These actives can be used together with peptides, but best results will come from cycling or alternating very strong actives in the evening. We suggest using peptides every morning with antioxidants, then switching every couple of nights with a peptide treatment, an AHA/BHA, and a retinoid if your skin can tolerate it.

• AHAs/BHAs. These exfoliating acids can be very potent. Since some acids break down peptide bonds, using strong exfoliants like glycolic or salicylic acid immediately before or after peptides can nullify their benefits. Either wait 15 minutes before using your peptide, or skip the treatment on exfoliation night. 
• Retinoids. Retinoids, like tretinoin or retinol, are actually a beautiful addition to the benefits of peptides. The skin turnover is greatly enhanced by these Vitamin A derivatives, and using peptides can soothe the skin afterward. Our board-certified dermatologists love these for a more advanced slow-aging ritual.